Issue : 01 DOI : 10.5281/zenodo.8147277

INTERNATIONAL

JOURNAL

DIAGNOSTICS

AND

RESEARCH

Volume : 01

Abstract

This study deals with evaluation of efficacy of Pashanbhed Choorna in the management of Mutrashmari. The main

aim of this particular study was to report the fast acting and cheapest Ayurvedic medicine for Mutrashmari. Study was

done in 55 patients who were suffering from Mutrashmari. Drug Pashanbhed Choorna was given to patients in dose

of 3 gms twice a day in Apankala (After food) with Koshnajal as Anupana. Study period was of 60 days. The patients

were assessed on the basis of subjective parameters i.e. Udarshool, Dahayukta Mutrapravrutti, Muhurmuhu

Mutrapravrutti and objective parameters i.e. USG Abdomen & pelvis. The result was satisfactory.

Keywords: Ayurveda, Mutrashmari, Pashanbhed Choorna

Corresponding author: Dr. Marathe Swapnil

Article Info: Published on : 15/04/2024

ISSN No. : 2584-2757

Volume : 01

Issue : 03

Publisher

ROGANIDAN VIKRUTIVIGYAN PG ASSOCIATION

FOR PATHOLOGY AND RADIODIGNOSIS

DOI

: 1 0 . 5 2 8 1 / z e n e d o . 1 1 0 9 4 2 9 1

Reg. No. : MAHA-703/16(NAG)

Year of Establishment – 2016

INTERNATIONAL JOURNAL OF DIAGNOSTICS AND RESEARCH

Clinical Study Of Efficacy Of Pashanbhed Choorna (Bhavprakash) In The

Management Of Mutrashmri.

Dr.Marathe Swapnil

, Dr.Pathrikar Anaya

PG Scholar, Department of Kayachikitsa, A.P.M. Ayurved Mahavidyalaya Sion, Mumbai-400022.

Professor & HOD, Department of Kayachikitsa, A.P.M. Ayurved Mahavidyalaya Sion, Mumbai-400022.

Cite this article as: - Dr. Marathe Swapnil (2024) ; Clinical Study Of Efficacy Of Pashanbhed Choorna (Bhavprakash) In The

Management Of Mutrashmri ; Inter.J.Dignostics and Research 1(3) 41-44, DOI: 10.5281/zenedo.11094291

Introduction:

There are four types of Mutrashmari according to

Shushruta Samhita i.e. Vataja, Pittaja, Shleshmaja

and Shukraj Ashmari and according to modern

science there are few types of renal calculi i.e. Uric

acid, calcium oxalate, calcium phosphate, calcium

carbonate, cystine, tyrosine. Mutrashmari is one

among the eight Mahagadas. The reason for

considering this disease as Mahagada is that, the

disease is Tridoshaja, Marmashrayee and its

Vyaktasthana is Basti which is one among

Dashavidha Pranayatana. Also sometimes, it is

fatal and it may need surgical intervention. The

incidence of Mutrashmari is rising day by day

around the world. It is affecting younger population

too. The first step we need to take is to bring

changes in diet and lifestyle patterns. Most

Mutrashmari can be treated without surgery.

In modern science; there are many treatment

modalities for urinary calculus like extra corporeal

shock wave lithotripsy (ESWL), Percutaneous

Nephro Lithotomy (PCNL), URS & Laser etc.

having their own merits and demerits. All these

procedures reduce the rate of open surgery in

urolithiasis. But these procedures are very costly

and limited to urban areas only. There are many

medicines described by Ayurved Samhitas, which

are greatly effective on Mutrashmari. Pashanbhed

Choorna is one of the drug explained by Acharya

Bhavprakash. This drug can be given on O.P.D.

basis and is administered without requiring

hospitalization. This is a non-invasive and safe drug

therapy.

Issue : 03

INTERNATIONAL JOURNAL OF DIAGNOSTICS AND RESEARCH [ISSN No.: 2584-2757]

Volume : 01

Aim and Objectives- To evaluate efficacy of

Pashanbhed Choorna with respect to Size of Renal

calculus, symptoms like Udarshool, Dahayukta

Mutrapravruti, Muhurmuhu Mutrapravruti.

Material And Method:

No.of patients-

55 Patients

Drug-

Pashanbhed Choorna

Duration of Study-

60 days

Dose-

3 gm twice a day

Route of administration-

Oral

Anupan-

Koshna jal 100ml

Kala-

centre of study-

Apankal

Ayurved Mahavidyalaya

and Seth R.V.Ayurved

Hospital sion Mumbai,

22.

Follow Up:

Clinical follow up was advised as:-

follow up 15

day

follow up 30

day

follow up 45

day

follow up 60

day

Inclusion Criteria:

1. Patient of Mutrashmari presenting with

Udarshool, Muhurmuhu Mutrapravrutti,

Dahayukta Mutrapravrutti of Mutrashmari

as per classics.

2. Patients between the age group of 18-60

years were selected irrespective of

occupation, religion and socio-economic

status.

3. Patients having size of calculi upto 15 mm.

Exclusion Criteria:

1. Patient having calculi size above 15mm.

2. Patients age below 18 years and above 60

years.

3. Patient having Mutrashmari associated with

Acute and Chronic kidney failure,

undergoing Chemotherapy, Radiation

therapy, major operative procedures and

pregnancy. Patients presenting with

obstructing renal calculi leading to

hydronephrosis.

Drug-Pashanbhed Choorna :

Preparation of Pashanbhed Choorna Material

for Choorna :

Aushadhi Dravya - Dry Choorna of Pashanbhed.

Procedure- Pashanbhed Choorna was mixed

properly and packed into packets.

Assessment Criteria :

Subjective Parameter- Classical sign and

symptoms of Mutrashmari were considered under

subjective parameters and for assessment of overall

effect of therapy.

a. Udarshool (Pain in abdomen)

b. Dahayukta Mutrapravrutti (Burning

micturition)

c. Muhurmuhu Mutrapravrutti (Dribbling

micturition)

Objective Parameter- Size of calculus

(Determined by USG-abdomen and pelvis)

Objective data was analyzed by using “z test” and

subjective data were analyzed by using “Mann -

Whitney-Wilcoxon U- Test.”

Gradation For Subjective Parameters:

In Udarshool (pain in abdomen) grade 0 for No

pain, grade 1 for intermittent pain, grade 2 for more

frequent pain, relieved with oral drugs and grade 3

for Excruciating pain, requiring parental drugs. In

Dahayukta Mutrapravrutti (Burning micturition)

grade 0 for no burning micturition, grade 1 for

mild, grade 2 for moderate and grade 3 for severe

burning micturition. In Muhurmuhu Mutrapravrutti

(Dribbling micturition) grade 0 for no dribbling

micturition, grade 1 for mild, grade 2 for moderate

and grade 3 for severe dribbling micturition.

Sr.

No.

Sanskrit

Name

Botanical

Name

Proportion

Pashanbhed

Bergenia

ligulata

1 Part

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INTERNATIONAL JOURNAL OF DIAGNOSTICS AND RESEARCH [ISSN No.: 2584-2757]

Volume : 01

Statistical Analysis :

1. Assessment of Udarshool-

2. Assessment of Dahayukta Mutrapravrutti-

3. Assessment of Muhurmuhu Mutrapravrutti-

4. Assessment of patients based on size of Calculi-

Discussion:

In Ayurvdic literature, various drugs described for

treatment of Mutrashmari, in which Pooshanbhed

Choorna was selected the median score of

Udarshool before treatment was 03 (range 01 to 03)

which has got changed to 1 (range 00 to 02). The

improvement in Udarshool On 60 days of treatment

with Pashanbhed Choorna was found to be

statistically significant. The median score of

Dahayukta Mutrapravrutti before treatment was 2

(range 01 to 03) which has got changed to 1 (range

00 to 02). The improvement in Dahayukta

Mutrapravrutti on 60 days of treatment with

Pashanbhed Choorna was found to be statistically

significant. The median score of Muhurmuhu

Mutrapravrutti before treatment was 01 (range 01 to

03) which has got changed to 01 (range 00 to 02).

Udarshool-BT

Udarshool - AT

Type of

Scale

Categorical -Ordinal

Sample Size

(n)

Mean ± SD

2.58 ± 0.60

1.05 ± 0.70

Median

Range

01 to 03

00 to 02

Statistical

Test

applied

Mann -Whitney-Wilcoxon U-

Test (Large Sample)

Mann -Whitney-Wilcoxon U- Test Statistic = 9.0168

P-Value

The two-tailed P-value is 0 <0.05

at 5% of level of significance,

considered extremely significant.

Inference

There is significant effect in

Udarshool after the treatment.

Dahayukta

Mutrapravrutti

-BT

Dahayukta

Mutrapravrutti-

Type of

Scale

Categorical -Ordinal

Sample Size

(n)

Mean ± SD

2.38 ± 0.62

0.89 ± 0.63

Median

Range

01 to 03

00 to 02

Statistical

Test applied

Mann -Whitney-Wilcoxon U-

Test (Large Sample)

Mann -Whitney-Wilcoxon U-

Test Statistic = 9.0108

P-Value

The two-tailed P-value is 0

<0.05 at 5% of level of

significance, considered

extremely significant.

Inference

There is significant effect in

Dahayukta Mutrapravrutti after

the treatment.

Muhurmuhu

Mutrapravrutti

-BT

Muhurmuhu

Mutrapravrutti

-AT

Type of Scale

Categorical -Ordinal

Sample Size (n)

Mean ± SD

1.47 ± 0.63

0.69 ± 0.57

Median

Range

00 to 03

00 to 02

Statistical Test

applied

Mann -Whitney-Wilcoxon U-

Test (Large Sample)

Mann -Whitney-Wilcoxon U-

Test Statistic = 8.0719

P-Value

The two-tailed P-value is 0 <

0.05 at 5% of level of

significance, considered

extremely significant.

Inference

There is significant effect in

Muhurmuhu Mutrapravrutti

after the treatment.

Size

Mean

Z-Value

P-Value

5.66

1.921051

0.259034

5.6608

3.67

3.047113

0.410873

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INTERNATIONAL JOURNAL OF DIAGNOSTICS AND RESEARCH [ISSN No.: 2584-2757]

Volume : 01

The improvement in Muhurmuhu Mutrapravrutti

on 60 days of treatment with Pashanbhed Choorna

was found to be statistically significant. There were

55 patients enrolled in which before treatment mean

calculi size was 5.66mm which reduced to 3.67mm.

Pashanbhed Choorna have Bhedan property.

Mutrala activities of Pashanbhed Choorna by

Sheeta Virya either promote or increase the amount

of urine excretion and helps in preventing the

Hyper-concentration of urine as well as further

complications.

Conclusion :

At the end of the study, it can be concluded that,

Pashanbhed Choorna is effective in relieving all

symptoms of Mutrashmari such as Udarshool,

Dahayukta Mutrapravrutti, Muhurmuhu

Mutrapravrutti as well as reduction in size of

Mutrashmari.

References:

1) P.V.Sharma; Sushruta Samhita; Published

by Chaukhamba Surbharati; Varanasi 2010;

Su.Ni.-3/3; Pg-481.

2) P.V.Sharma; Sushruta Samhita; Published

by Chaukhamba Visvabharati; Varanasi

2010; Su.Ni.-3/4; Pg-481.

3) Bhavmisra; Bhavprakash Nighantu;

Published by chaukhamba Sanskrit bhavan;

Harityadi varg; Pg.105

4) Prof.Dr.P.H.Kulkarni; Research

Methodology for students in Ayurveda 1st

2000; Published by Ayurveda Research

Institute.

ISSN : 2584-2757

DOI : 10.5281/zenedo.11094291

Dr. Marathe Swapnil Inter. J.Digno. and Research

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